Pharmaceutical Machinery

Sensors That Withstand Sterilisation, High-Heat, and Dust-Loaded Zones

In pharmaceutical machinery, regulated measurement accuracy is essential for safe and compliant operation. From differential pressure in laminar-flow hoods to critical airflow in isolators, moisture control in dryers, and process-gas monitoring in packaging machines, sensors must deliver stable readings under harsh conditions. E+E Elektronik sensors are engineered to support compliance with GMP guidelines and, where required, ATEX/IECEx standards. Hydrogen peroxide sterilisation, high temperatures, solvents, and dusty or explosive atmospheres quickly push standard sensors to their limits, leading to drift, frequent servicing, and complex multi-supplier validation.

  • Catalytic H₂O₂ filter caps, stainless-steel housings, and E+E’s proprietary sensor coating ensure long-term stability under aggressive cleaning
  • EN ISO/IEC 17025-accredited calibration with BEV/E+E designation provides NMI-level traceability and compliant documentation
  • Auto-zero differential pressure, modular probes, and digital interfaces support fast commissioning and stable operation
  • One partner offering a complete sensor suite with global support reduces supplier complexity and simplifies validation
+ 65 countries supported with local E+E experts & service
180 °C operating capability in high-temperature drying systems
6 critical measurands covered by one supplier

Advantages of E+E Sensors in Pharmaceutical Machinery

In pharmaceutical machinery, sensors must endure frequent sterilisation, aggressive cleaning, and 24/7 operation. Extreme humidity levels, solvents, and thermal cycling often cause sensor drift and performance degradation over time. E+E sensors are developed and manufactured entirely in-house from the sensing element to the assembled transmitter. This vertical integration provides full control over all materials and process steps, delivering outstanding long-term stability and reliability in demanding pharmaceutical environments.

Sterilisation with hydrogen peroxide (H₂O₂), alcohol-based cleaning, solvent exposure, and temperature extremes place extreme stress on sensitive measurement components.
E+E sensors are engineered to withstand these stresses through:

  • Protective sensor coatings and filters that shield humidity and temperature sensing elements from solvents and chemical residues.
  • ARC (Automatic ReCovery) that actively restores sensor performance after exposure to alcohols or cleaning vapours.
  • Catalytic H₂O₂ filters to prevent degradation during bio-decontamination cycles.
  • Ceramic-based sensing elements in air-velocity probes offering exceptional mechanical and chemical stability.
  • Stainless-steel housings and interchangeable filter caps providing durable protection against corrosion and contamination build-up.

This robustness ensures consistent performance when sterility and uptime are critical.

Machine builders in the pharmaceutical sector require multiple measurement parameters, yet prefer a single trusted partner. Managing several instrument suppliers increases validation effort and complicates documentation. E+E Elektronik provides a comprehensive sensor portfolio for humidity, temperature, differential pressure, air velocity, air flow and dew point. A unified platform design simplifies mechanical and electrical integration, reduces qualification time, and ensures consistent quality across all parameters.

Regulated industries demand verifiable accuracy and documented compliance. Calibration uncertainty or non-traceable certificates can lead to costly requalification or audit findings. E+E sensors are calibrated in the company’s EN ISO/IEC 17025-accredited, in-house laboratory, traceable to national metrology institute (NMI) standards. Each device ships with complete, traceable documentation, providing the certainty and transparency required for GMP, FDA-regulated environments, and ATEX/IECEx-classified zones.

Modern pharmaceutical machines rely on seamless data integration and minimal downtime. E+E sensors feature auto-zero calibration and a modular digital platform such as Sigma 05 with USB-C configuration and bus connectivity. These innovations ensure consistent process control, fast calibration checks, and straightforward integration into existing control architectures.

Products for Pharmaceutical Machinery

AVS701 – Highly accurate air and gas velocity sensor for industrial applications | E+E Elektronik

AVS701

Highly Accurate Air and Gas Velocity Sensor for Industrial Applications

  • -40 to +140 °C (-40 °F to 284°F)
  • 0 to 40 m/s (0 to 8 000ft/min)
  • IP65 / NEMA 4X
  • for demanding industrial applications
  • high-end ceramic sensing element
  • stainless steel sensor head and probe
  • Modbus RTU
HTS801 humidity and temperature sensor

HTS801

Humidity and Temperature Sensor for High Humidity and Chemically Polluted Conditions

  • -80 °C to 180 °C (-112 °F to 356 °F)
  • 300 bar (4 350 psi)
  • RS485 (Modbus RTU)
  • E+E proprietary coating
  • IP65 / NEMA 4
  • polycarbonate or stainless-steel enclosure
  • several probe and cable lengths available
  • for chemical contamination
  • for continuous high humidity conditions

HTS401

Modular Humidity and Temperature Sensor for Demanding Climate Control

  • -40 to +80 °C (-40 to +176 °F)
  • 0–100 % RH
  • ±0.95 % RH / ±0.1 °C (0.18 °F)
  • analog outputs (0–5 V / 0–10 V / 4–20 mA)
  • RS485 (Modbus RTU)
  • E+E proprietary coating
  • IP65 / NEMA 4(X)
  • for high humidity and chemical exposure
EE300Ex Humidity transmitter for intrinsically safe applications

EE300Ex

Humidity and Temperature Sensor for Intrinsically Safe Applications

  • -40 to +180 °C (-40 to +356 °F)
  • 2-wire 4–20 mA
  • intrinsically safe (ATEX / IECEx / FM / NEPSI / KCs)
  • E+E proprietary coating
  • Pressure tight up to 20 bar (300 psi)
  • IP65 / NEMA 4
  • for explosive gas and dust atmospheres
  • Stainless steel enclosure and probe
HTP501 - Digital Humidity and Temperature Probe

HTP501

Digital Humidity and Temperature Probe up to 120 °C (248 °F)

  • 0–100 % RH
  • −40 to +120 °C (−40 to +248 °F)
  • E+E proprietary coating
  • stainless-steel enclosure
  • Modbus RTU
  • M12 connector

EE680

Air Velocity and Temperature Sensor for Laminar Flow

  • 0 to 2 m/s (0 to 400 ft/min)
  • -20 to +70 °C (-4 to +158 °F)
  • analog outputs (0–5 V / 0–10 V / 0–20 mA / 4–20 mA)
  • Modbus RTU
  • resistance against H₂O₂
  • LED ring for status indication

EE660

Low Air Velocity Sensor

  • 0 to 2 m/s
  • RS485 (Modbus RTU)
  • hot-film anemometer thin-film sensor element
  • low-velocity measurement from 0.15 m/s (30 ft/min)
  • IP65 / NEMA 4X

EE610

Low Differential Pressure Sensor

  • 0...25 / 50 / 75 / 100 Pa
  • –20…60 °C (–4…140 °F)
  • Accuracy: ±0.5 Pa = ±0.5 % FS
  • Auto-zero function
  • Analogue output: 0–10 V or 4–20 mA
  • Modbus RTU (RS485)
  • IP65 / NEMA 4X housing

EE576

Probe for Very Low Air Velocity

  • 0.1 / 2 m/s (200 / 400 ft/min)
  • −20 to +60 °C (−4 to +140 °F)
  • analogue outputs (0–5 V / 0–10 V)
EE072 humidity and temperature probe with digital interface

EE072

Humidity and Temperature Probe with Digital Interface

  • 0 ... 100 %RH
  • -40 ... 80 °C (-40 ... 176 °F)
  • E+E proprietary coating
  • Polycarbonate or stainless steel
  • Modbus RTU / CANopen
  • ±1.3 % / ±2.3 % RH accuracy
Omniport 40 | Multifunctional hand-held meter

Omniport 40

Multifunctional Hand-Held Meter

  • 2x 5-pin M12 connection
  • Up to 1 million measuring points
  • USB-C interface
  • 4x AA rechargeable NiMH batteries
  • IP67 protection rating
  • connection of up to 2 probes
Sigma 05 - Modular Sensor Platform

Sigma 05

Modular Sensor Platform

  • up to 3 sensing probes
  • up to 5 measurands
  • polycarbonate or metal enclosure
  • IP65 / NEMA 4X

Application areas for Pharmaceutical Machinery

Precise airflow control for sterile environments.

Reliable sensor technology for RABS, isolators, and aseptic containment systems.

Accuracy and stability for pharmaceutical drying processes.

Pharmaceutical Packaging and Filling Machinery

Read more about Pharmaceutical Packaging and Filling Machinery

Reliable gas flow and dew point measurement for process gases in filling and packaging machines.

Optimised Measurement in Pharmaceutical Machinery

Improve compliance, reduce drift and simplify validation with robust, GMP-ready sensors for every critical parameter.

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Questions about Pharmaceutical Machinery?

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Matthew Nemeth | Managing Director E+E Elektronik Corporation USA
Matthew Nemeth | Managing Director E+E Elektronik Corporation USA
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